Article (Scientific journals)
Gold-coated tilted fiber Bragg gratings for lead ion sensing.
Zhu, Tianbo; Loyez, Médéric; Chah, Karima et al.
2023In Optics Express, 31 (20), p. 32478 - 32487
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Keywords :
Aptamers; Functionalizations; Gold layer; Gold-coated; Ion sensing; Label-free biosensing; Lead ions; Refractometry; Surface plasmon resonance sensor; Tilted fiber Bragg grating; Atomic and Molecular Physics, and Optics
Abstract :
[en] Surface plasmon resonance sensor based on gold-coated tilted fiber Bragg gratings (SPR-TFBGs) are perfectly suited for fine refractometry. Thanks to the functionalization of the gold layer, they can be used for label-free biosensing. They have been largely used for the specific detection of proteins and cells. In this work, we experimentally demonstrate that they are enough sensitive to detect a very small entity like an environmental pollutant. In this context, we report here a bio-functionalization of the SPR-TFBG with thrombin aptamers for lead ion detection. We used aqueous solutions of lead ions with increasing concentrations from 0.001 ppb to 10 ppb. Based on the affinity bending of Pb2+ ions to the thrombin aptamer, we experimentally demonstrated low detection level of lead ion concentration (0.001 ppb) while the saturation limit is meanly fixed by the physical dimension of the sensor and the binding efficiency.
Disciplines :
Engineering, computing & technology: Multidisciplinary, general & others
Author, co-author :
Zhu, Tianbo  ;  Université de Mons - UMONS > Recherche > Service ERC Unit - Advanced Photonic
Loyez, Médéric  ;  Université de Mons - UMONS > Faculté des Science > Service de Protéomie et Microbiologie
Chah, Karima  ;  Université de Mons - UMONS > Recherche > Service ERC Unit - Advanced Photonic
Caucheteur, Christophe  ;  Université de Mons - UMONS > Faculté Polytechniqu > Service d'Electromagnétisme et Télécommunications
Language :
English
Title :
Gold-coated tilted fiber Bragg gratings for lead ion sensing.
Publication date :
25 September 2023
Journal title :
Optics Express
eISSN :
1094-4087
Publisher :
Optica Publishing Group (formerly OSA), United States
Volume :
31
Issue :
20
Pages :
32478 - 32487
Peer reviewed :
Peer Reviewed verified by ORBi
Research unit :
F108 - Electromagnétisme et Télécommunications
Research institute :
Biosciences
Funders :
Fonds De La Recherche Scientifique - FNRS
Funding text :
Fonds De La Recherche Scientifique - FNRS.
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since 24 November 2023

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