Changes in morphology and function of adrenal cortex in mice fed a high-fat 
diet.

Swierczynska, Marta Maria; Mateska, Ivona; Peitzsch, M; Bornstein, Stefan; Chavakis, Trian; Eisenhofer, G; Lamounier-Zepter, Valéria; Eaton, Suzanne

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Changes in morphology and function of adrenal cortex in mice fed a high-fat diet.

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Swierczynska, Marta Maria
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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Mateska, Ivona
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

Bornstein, Stefan
Max Planck Society;

Chavakis, Trian
Max Planck Society;

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Eaton, Suzanne
Max Planck Institute of Molecular Cell Biology and Genetics, Max Planck Society;

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引用

Swierczynska, M. M., Mateska, I., Peitzsch, M., Bornstein, S., Chavakis, T., Eisenhofer, G., Lamounier-Zepter, V., & Eaton, S. (2015). Changes in morphology and function of adrenal cortex in mice fed a high-fat diet. International Journal of Obesity (2005), 39(2), 321-330.

引用: https://hdl.handle.net/21.11116/0000-0001-040A-0

要旨

Obesity is a major risk factor for the development of type 2 diabetes and other debilitating diseases. Obesity and diabetes are intimately linked with altered levels of adrenal steroids. Elevated levels of these hormones induce insulin resistance and cause cardiovascular diseases. The mechanisms underlying obesity-related alterations in adrenal steroids are still not well understood. Here, we investigated how diet-induced obesity affects the morphology and function of the mouse adrenal cortex.