[en] The new guidelines from the European Atherosclerosis Society and the European Society of Cardiology include a number of new items. Here we demonstrate their application in several different clinical examples. We focus on the 4 items most pertinent for medical practice: 1) the stratification of risk of cardiovascular disease into 4 categories ('very high', 'high', 'moderate' and 'low risk'), involving--for primary prevention cases--the use of the SCORE table, which has been calibrated for Belgium and where the risk can be adjusted according to HDL cholesterol and the presence of other risk factors; 2) the choice of more stringent therapeutic targets for LDL cholesterol (< 70 mg/dl for 'very high' risk patients, 100 mg/dl for 'high' risk patients and 115 mg/dl for patients at 'moderate' risk); 3) the choice of other therapeutic targets (non-HDL cholesterol and apolipoprotein B levels) for patients at 'very high' or 'high' risk with combined dyslipidaemia; and 4) follow-up of lipid parameters and muscular and hepatic enzymatic profiles.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Descamps, O. S.
SCHEEN, André ; Centre Hospitalier Universitaire de Liège - CHU > Diabétologie,nutrition, maladies métaboliques
De Backer, G.
Annemans, L.
Muls, E.
Language :
French
Title :
Comment je traite ... une dyslipidemie en fonction du profil de risque cardiovasculaire.
Alternative titles :
[en] How I treat ... dyslipidaemia according to the cardiovascular risk profile
Publication date :
2012
Journal title :
Revue Médicale de Liège
ISSN :
0370-629X
eISSN :
2566-1566
Publisher :
Université de Liège. Revue Médicale de Liège, Liège, Belgium
Reiner Z, Catapano AL, De Backer G, et al. - ESC/EAS Guidelines for the management of dyslipidaemias : the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). European Association for Cardiovascular Prevention & Rehabilitation. Eur Heart J, 2011, 32, 1769-1818.
Descamps OS, De Backer G, Muls E, Scheen AJ, Belgian Atherosclerosis Society/ Belgian Lipid Club. - Les nouvelles recommandations européennes pour le traitement des dyslipidémies en prévention cardiovasculaire. Rev Med Liège, 2012, 67.
INAMI. - Usage et prescription des statines 2010. http://www.inami.be/ drug/fr/drugs/recommendation/pdf/table-statines.pdf
Descamps O, Cooney MT, Graham I, De Backer G. - A simple multiplier to calculate the impact of HDL cholesterol on cardiovascular risk estimation using SCORE. Atherosclerosis, 2012, Submitted.
Descamps OS, Tenoutasse S, Stephenne X, et al. - Management of familial hypercholesterolemia in children and young adults : consensus paper developed by a panel of lipidologists, cardiologists, paediatricians, nutritionists, gastroenterologists, general practitioners and a patient organization. Atherosclerosis, 2011, 218, 272-280.
Paquot N, Scheen AJ. - Quelles cibles glycémiques et lipidiques viser chez un patient diabétique de type 2 ? Rev Med Liège, 2012, 67, 98-103.
Scheen AJ, Kulbertus H. - Prévention cardiovasculaire par les statines : faut-il encore doser le cholesterol ? Rev Med Liège, 2003, 58, 191-197. (Pubitemid 37013903)
Ducobu J, Scheen A, Van Gaal L, et al. - Belgian expert opinion : how to reduce the residual risk in atherogenic-dyslipidaemic patients : place of fibrates. Acta Cardiol, 2008, 63, 235-248. (Pubitemid 351548712)
Scheen AJ, Radermecker RP. - Ezétimibe (Ezetrol®) chez le patient diabétique. Rev Med Liège, 2009, 64, 606-611.
Radermecker RP, Scheen AJ. - Comment optimaliser le traitement hypolipidémiant : ne pas oublier la problématique du défaut d'observance. Rev Med Liège, 2010, 65, 311-317.
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