Parasitic worms affect virus coinfection: a mechanistic overview.

[en] Helminths are parasitic worms that coevolve with their host, usually resulting in long-term persistence through modulating host immunity. The multifarious mechanisms altering the immune system induced by helminths have significant implications on the control of coinfecting pathogens such as viruses. Here, we explore the recent literature to highlight the main immune alterations and mechanisms that affect the control of viral coinfection. Insights from these mechanisms are valuable in the understanding of clinical observations in helminth-prevalent areas and in the design of new therapeutic and vaccination strategies to control viral diseases.

Disciplines :

Immunology & infectious disease

Author, co-author :

Petrellis, Georgios ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH)

Piedfort, Ophélie ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Santé publique vétérinaire

Katsandegwaza, Brunette ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Immunologie vétérinaire

Dewals, Benjamin G ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Immunologie vétérinaire

Language :

English

Title :

Parasitic worms affect virus coinfection: a mechanistic overview.

Publication date :

17 March 2023

Journal title :

Trends in Parasitology

ISSN :

1471-4922

eISSN :

1471-5007

Publisher :

Elsevier BV, England

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://api.elsevier.com/content/article/PII:S1471492223000405?httpAccept=text/xml

Available on ORBi :

since 22 March 2023

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