Efficacy of the Adjunct Use of Povidone-Iodine or Sodium Hypochlorite with Non-Surgical Management of Periodontitis: A Systematic Review and Meta-Analysis.
El Mobadder, Marwan; Namour, Samir; Grzech-Leśniak, Zuzannaet al.
2022 • In Journal of Clinical Medicine, 11 (21), p. 6593
NaOCl; PVP-I; non-surgical; periodontal therapy; periodontitis; povidone-iodine; sodium hypochlorite; Medicine (all); General Medicine
Abstract :
[en] This systematic review sought to assess the efficacy of combining either sodium hypochlorite or povidone-iodine as disinfection solutions with non-surgical treatment of periodontitis. An electronic search was conducted through PubMed, Scopus, Web of Science, CENTRAL, and Google Scholar from inception until 10 September 2022. Outcomes included clinical outcomes (probing pocket depth, plaque index, clinical attachment level, relative-horizontal attachment level, bleeding on probing, gingival recession, the position of gingival margin) and biochemical (BAPNA level) properties. A subgroup analysis was conducted according to the assessment timepoint. Ten studies reporting the use of povidone-iodine and five studies reporting the use of sodium hypochlorite were included in this review. Overall, in the meta-analysis of povidone-iodine, no significant changes were noted in any of the assessed outcomes; however, minor changes were noted in probing pocket depth and clinical attachment level at a specific timepoint. Regarding sodium hypochlorite, a significant reduction in all clinical outcomes, except for bleeding on probing, was noted. In conclusion, the use of povidone-iodine does not result in an improvement in clinical outcomes, whereas sodium hypochlorite has promising properties that result in significant improvement in probing pocket depth and clinical attachment level. However, more studies are needed to confirm these observations.
Disciplines :
Dentistry & oral medicine
Author, co-author :
El Mobadder, Marwan ; Dental Surgery Department, Wroclaw Medical University, 50-425 Wroclaw, Poland
Namour, Samir ; Université de Liège - ULiège > Département des sciences dentaires
Grzech-Leśniak, Zuzanna; Dental Surgery Department, Wroclaw Medical University, 50-425 Wroclaw, Poland
Grzech-Leśniak, Kinga ; Dental Surgery Department, Wroclaw Medical University, 50-425 Wroclaw, Poland
Language :
English
Title :
Efficacy of the Adjunct Use of Povidone-Iodine or Sodium Hypochlorite with Non-Surgical Management of Periodontitis: A Systematic Review and Meta-Analysis.
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