Aging; Exercise; HIIT; Nutrition; Obesity; Orthopedics and Sports Medicine; Physical Therapy, Sports Therapy and Rehabilitation; General Medicine
Abstract :
[en] A 12-week intervention involving high-intensity interval training (HIIT) with or without citrulline (CIT) supplementation induced adaptations in the serum metabolome of obese older adults through significant changes in 44 metabolites.Changes in 23 metabolites were observed when a CIT supplementation was administered along with a 12-week HIIT intervention.TG (16:1/18:1/16:0) correlated with several adiposity parameters including leptin, triglycerides, legs lean mass.Aspartic acid correlated with several adiposity parameters including leptin, LDL cholesterol as well as android, arms and trunk fat mass.
Disciplines :
Geriatrics
Author, co-author :
Youssef, Layale ; T3S INSERM U1124, Université Paris Cité, Paris, France ; École de Kinésiologie et des Sciences de l'Activité Physique (EKSAP), Université de Montréal, Montréal (QC), Canada ; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada
Durand, Sylvère; INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France ; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, AMMICa US23/CNRS UMS3655, Villejuif, France
Aprahamian, Fanny; INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France ; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, AMMICa US23/CNRS UMS3655, Villejuif, France
Lefevre, Deborah; INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France ; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, AMMICa US23/CNRS UMS3655, Villejuif, France
Bourgin, Melanie; INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France ; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, AMMICa US23/CNRS UMS3655, Villejuif, France
Maiuri, Maria Chiara; INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France ; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, AMMICa US23/CNRS UMS3655, Villejuif, France
Dulac, Maude; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada ; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Département de biologie, Université du Québec à Montréal, Montréal, Canada ; Research Institute of the McGill University Health Center (MUHC), Montréal (QC), Canada
Hajj-Boutros, Guy; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Research Institute of the McGill University Health Center (MUHC), Montréal (QC), Canada
Marcangeli, Vincent; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada ; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Département de biologie, Université du Québec à Montréal, Montréal, Canada
Buckinx, Fanny ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé ; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada ; Département des sciences de l'activité physique, Université du Québec à Montréal, Montréal, Canada
Peyrusqué, Eva; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada ; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Département des sciences de l'activité physique, Université du Québec à Montréal, Montréal, Canada
Morais, José A; Research Institute of the McGill University Health Center (MUHC), Montréal (QC), Canada
Gaudreau, Pierrette; Centre de Recherche du Centre Hospitalier de l'Université de Montréal, Université de Montréal, Montréal (QC), Canada ; Département de Médecine, Université de Montréal, Montréal (QC), Canada
Gouspillou, Gilles; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada ; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Département des sciences de l'activité physique, Université du Québec à Montréal, Montréal, Canada
Kroemer, Guido; INSERM U1138, Centre de Recherche des Cordeliers, Sorbonne Université, Université Paris Cité, Paris, France ; Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, AMMICa US23/CNRS UMS3655, Villejuif, France
Aubertin-Leheudre, Mylène; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal (CRIUGM), Montréal, Canada ; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Département des sciences de l'activité physique, Université du Québec à Montréal, Montréal, Canada
Noirez, Philippe; T3S INSERM U1124, Université Paris Cité, Paris, France ; Groupe de Recherche en Activité Physique Adaptée, Université du Québec à Montréal, Montréal, Canada ; Département des sciences de l'activité physique, Université du Québec à Montréal, Montréal, Canada ; UFR STAPS, Performance Santé Métrologie Société (PSMS), Université de Reims Champagne Ardenne, Reims, France ; Institut de Recherche Médicale et d'Épidémiologie du Sport (IRMES), INSEP, Université Paris Cité, Paris, France
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